SLU-PP-332 siv rau dab tsi?
Hauv kev xaus, ERR agonist SLU-PP-332 ua haujlwm raws li kev tawm dag zog mimetic inducing ib qho kev mob aerobic ce uas ua rau myriad physiologic adaptations uas cuam tshuam nrog kev tawm dag zog nrog rau cov pob txha pob txha oxidative fibers, nce fatty acid oxidation, thiab txhim khu kev ua kom muaj zog.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
Luv Lus Qhia Txog
SLU-PP-332 yog cov khoom siv hluav taws xob me me, muaj peev xwm tsis xaiv cov tshuaj estrogen-associated receptor (ERR) agonist, uas muaj qhov muaj zog tshaj plaws ntawm ERRα, nrog EC50 ntawm 98 nM. SLU-PP-332 tau txhawb nqa kev txaus siab ntawm kev tshawb fawb biomedical vim nws cov kev siv tau zoo hauv kev noj qab haus huv metabolic thiab simulation.
MF: C18H14N2O2
MW: 290.32 ib
CAS: 303760-60-3
Qhov ceev: 1.20 ± 0.1 g / cm³ (Predicted)
Cia txias: 2-8 ° C
Solubility ntawm DMSO: 2mg / mL, ntshiab (sov)
Acidity coefficient (pKa): 8.44 ± 0.15 (Predicted)
Mechanism of Action
SLU-PP-332 ua haujlwm raws li ERRα agonist, txhim kho kev ua haujlwm mitochondrial thiab lub zog metabolism. Nws ua lub luag haujlwm tseem ceeb hauv kev tswj cov roj oxidation, qabzib metabolism, thiab thermogenesis, ua rau nws muaj peev xwm los kho cov kab mob metabolic. Lub compound khi rau ligand-binding domain ntawm ERRα, stabilizing nws nquag conformation thiab txhim kho nws kev sib raug zoo nrog coactivator proteins, tshwj xeeb tshaj yog PGC-1α (peroxisome proliferator-activated receptor gamma coactivator 1-alpha).
Kev tshawb nrhiav thiab kev siv
SLU-PP-332 tau raug sim hauv ntau qhov kev tshawb fawb ua ntej, suav nrog nws lub peev xwm los: Txhim kho cov kab mob metabolic los ntawm kev txhim kho mitochondrial efficiency. Induce ce-mimetic teebmeem hauv cov leeg nqaij. Reverse age-related mitochondrial dysfunction. SLUPP-332 tuaj yeem txhim kho mitochondrial muaj nuj nqi thiab kev ua pa ntawm tes, nce hom IIa oxidized skeletal nqaij fibers, thiab txhim khu kev ua haujlwm siab ntawm cov leeg pob txha ntawm tes. SLU-PP-332 muaj peev xwm siv tau rau hauv kev tshawb fawb ntawm cov kab mob metabolic thiab txhim kho cov leeg nqaij, thiab tseem tuaj yeem siv los txhim kho cov kab mob metabolic thiab kev laus.
Qhov teebmeem kev lom neeg
Metabolic Syndrome thiab Obesity
Cov kev tshawb fawb hauv cov qauv tsiaj tau pom tias SLU-PP-332 txhim kho insulin rhiab heev thiab txo cov adiposity, qhia nws lub peev xwm ua tshuaj tiv thaiv rog. SLU-PP-332 ua:
18-24% txo qis hauv lub cev hnyav.
30-35% txo qis hauv cov ntaub so ntswg dawb.
40% kev txhim kho hauv qabzib kam rau ua.
25-30% txo qis hauv cov tshuaj insulin sai.
Kev txo qis hauv hepatic steatosis thiab o.
Cov txiaj ntsig ntawm SLU PP yog dab tsi?
SLU-PP-332 yog ib yam tshuaj uas ua raws li cov txiaj ntsig ntawm kev tawm dag zog, coj mus rau kev siv zog ntxiv thiab ze zog lub cev rog metabolism. pib kev tawm dag zog. Tus neeg sawv cev no txhim kho txoj hauv kev hauv lub cev uas muaj cov yam ntxwv ua rau kev tawm dag zog, ua rau muaj zog siv zog, thiab ntxiv cov roj metabolism hauv lub cev.
Puas yog SLU-PP-332 ua haujlwm?
Kev tshawb fawb thawj zaug tau tsom mus rau cov nas qhov hnyav thiab qhia qee qhov txiaj ntsig zoo nkauj. Cov nas uas tau kho nrog SLU-PP-332 tuaj yeem khiav tau 70% ntev dua thiab 45% ntxiv dua li lawv cov neeg tsis kho. Uas zoo li mus los ntawm NW nyuam qhuav ua nws ib ncig ntawm lub thaiv kom dheev npaj txhij rau ib nrab-marathon!
Cov kev mob tshwm sim ntawm SLU-PP-332 yog dab tsi?
Tej yam tshwm sim tshwm sim: Cov tsos mob pom muaj xws li mob me me hyperthermia, nce lub plawv dhia, thiab kev hloov pauv hauv daim siab enzymes hauv kev tshawb fawb tsiaj.
SLU-PP-332 yog dab tsi?
| Pob loj | nqe |
| 1g | USD 50 |
| 5g | USD 239 |
| 10g | USD 388 |
| 50g | USD 1,458 |
| 100g | USD 2,498 |
Thov qhia rau peb paub qhov chaw nyob shipping kom peb tuaj yeem xa tus nqi xa tuaj rau koj.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
Yav Tom Ntej Cov Kev Qhia
Kev tshawb fawb ntawm SLU-PP-332 thiab lwm yam ERR modulators txuas ntxiv mus rau qhov chaw kho tshiab:
Neurodegeneration: Cov kev tshawb fawb ua ntej qhia tias muaj peev xwm siv tau hauv Alzheimer's thiab Parkinson's kab mob los ntawm kev txhim kho mitochondrial.
Cancer metabolism: Kev tshawb xyuas rau lub luag haujlwm ntawm ERR teeb liab hauv cov qog ua kom muaj zog thiab muaj peev xwm kho tau.
Kev tshawb fawb ntev: Kev tshawb fawb ntawm ERR ua kom muaj peev xwm cuam tshuam los txuas ntxiv kev noj qab haus huv.
Cov tshuaj kho tus kheej: Kev txhim kho biomarkers txhawm rau txheeb xyuas cov neeg mob feem ntau yuav teb rau ERR-targeted kev kho mob.
1. Koj puas muaj teeb meem xa tuaj rau kuv lub tebchaws?
A: Peb muaj warehouses nyob teb chaws Europe, America thiab Australia. Nyob rau tib lub sijhawm, yog tias koj tuaj ntawm Tebchaws Europe, cov khoom tuaj yeem xa los ntawm lub teb chaws Yelemees, thiab yog tias koj los ntawm Asmeskas lossis Canada, cov khoom tuaj yeem xa los ntawm California.
2. Cov khoom ntim li cas?
A: Peb feem ntau xa cov khoom nrog cov khoom pov tseg sab nraud thiab ob txheej txheej sterile pob tshab hauv lub hnab.Peb tau sim ntau txhiab txoj hauv kev, nws zoo li hnyav thiab tsis pom kev.
3. Thaum twg koj yuav xa cov khoom tom qab them nyiaj tiav?
A: Feem ntau qhov kev txiav txim yuav xa tuaj tsis pub dhau 2-3 hnub tom qab qhov kev txiav txim tau lees paub, tshwj tsis yog cov khoom lag luam customized.
4. Yuav ua li cas mus txiav txim?
A: Thov cia kuv paub cov khoom koj tab tom nrhiav, kom muaj nuj nqis thiab lub teb chaws qhov chaw uas pab kuv muab tus nqi tsim nyog; Tom qab koj paub meej tias tag nrho cov ntsiab lus ntawm kev txiav txim, them nyiaj ua ntej thiab muab qhov chaw nyob Shipping rau peb.Peb npaj cov khoom xa tuaj thaum thawj zaug tom qab tau txais cov nyiaj them poob haujlwm thiab muab kev pab cuam tom qab muag tom qab koj tau txais parcel.
